30 March 2023: Textbook Updates
We have posted updates of the following topics: Breast > Sarcoma > Angiosarcoma by Sofia Lérias, M.D., Melinda Lerwill, M.D. Topic summary: Malignant vascular neoplasm, which may arise in previously irradiated skin or breast tissue (secondary postradiation angiosarcoma) or in nonirradiated tissue (primary angiosarcoma). Irregular, infiltrative anastomosing vascular channels with endothelial atypia; postradiation angiosarcoma demonstrates…
28 March 2023: Case of the Month #525
Thanks to Dr. Carlos A. Torres-Cabala, University of Texas MD Anderson Cancer Center, Houston, Texas, USA for the images; Drs. Alessia Cimadamore and Rodolfo Montironi, Polytechnic University of the Marche Region, Ancona, Italy and the Genitourinary Pathology Society (GUPS) for the discussion; and Dr. Jonathan Ho, The University of the West Indies, Mona, Jamaica for reviewing the…
27 March 2023: Textbook Updates
We have posted updates of the following topics: Bone marrow neoplastic > Bone marrow – neoplastic myeloid > Recurrent genetic abnormalities > APL with PML::RARA by Haley Amoth, M.D., Anamarija M. Perry, M.D. Topic summary: Acute myeloid leukemia (AML) with predominance of abnormal promyelocytes and fusion of the promyelocytic leukemia (PML) gene with the retinoic…
24 March 2023: Weekly Roundup #116
Here’s what you need to know about PathologyOutlines.com this week: 1. 2022 Year in Review Video We have posted a YouTube video highlighting the significant changes that were made to PathologyOutlines.com in 2022. View it at https://www.youtube.com/watch?v=itFpiInjRrQ. 2. What’s New in Bone and Soft Tissue Pathology E-Newsletter Make sure to sign up for our What’s New…
23 March 2023: Textbook Updates
We have posted updates of the following topics: Breast > Epithelial-myoepithelial tumors > Myoepithelioma and myoepithelial carcinoma by Harsh Batra, M.B.B.S., D.C.P., D.N.B., Julie M. Jorns, M.D. Topic summary: Myoepithelioma: bland spindle cell lesion with myoepithelial phenotype; myoepithelial carcinoma: very rare malignant lesion, mostly arising in association with adenomyoepitheliomas, composed of purely malignant myoepithelial cells,…
21 March 2023: Image Quiz #104
Authors: Truong Phan Xuan Nguyen, M.D., Ichizo Nishino, M.D., Ph.D. Glycogen storage disease type V (GSD V, McArdle disease) causes muscle cramps, muscle fatigue and increased muscle glycogen. Which of the following enzymes is deficient? Select an answer: A. Hepatic hexokinase B. Muscle debrancher enzyme C. Muscle hexokinase D. Muscle phosphofructokinase E. Muscle phosphorylase To sign…
17 March 2023: Weekly Roundup #115
Here’s what you need to know about PathologyOutlines.com this week: 1. Informatics We are strengthening our Informatics, digital & computational pathology chapter with our revised topic on AP Laboratory information systems by Drs. Jonah and Parwani. Let Dr. Pernick know of any suggested new topics at Nat@PathologyOutlines.com. 2. Image Contest We have started a contest for the…
16 March 2023: Textbook Updates
We have posted updates of the following topics: Breast > Other invasive carcinoma subtypes, WHO classified > Apocrine by Jonathan Marotti, M.D. Topic summary: Invasive breast carcinoma comprised of large cells with abundant eosinophilic and granular cytoplasm, enlarged nuclei and prominent nucleoli; apocrine morphology in > 90% of tumor cells. Estrogen receptor (ER) negative, progesterone…
13 March 2023: Textbook Updates
We have posted updates of the following topics: Liver & intrahepatic bile ducts > Developmental anomalies / cysts > Simple biliary cyst by Lokman Cevik, M.D., Wei Chen, M.D., Ph.D. Topic summary: Unilocular fluid filled intrahepatic cysts that do not communicate with the intrahepatic biliary tree. Most common hepatic cyst, F > M; prevalence increases…
10 March 2023: USCAP 2023
PathologyOutlines.com is pleased to attend USCAP 2023 in New Orleans on March 13 – 15. Stop by booth #122 for our great felt tip markers and other giveaways. Review or add your Directory profile and vote for our Directory image contest. Pose for a picture or record a video. Sign up for our What’s New or other newsletters. Learn…
9 March 2023: Textbook Updates
We have posted updates of the following topics: Autopsy & forensics > General > Brain contusions by Michel Tawil, M.D., Christine E. Fuller, M.D. Topic summary: Focal injuries to the brain occurring at locations where brain tissue directly impacts against the inner skull / bony protuberances. Can bleed into the cerebrospinal fluid (CSF), causing subarachnoid…
7 March 2023: Image Quiz #103
Author: Sarah H. Glass, D.D.S. A biopsy of a lesion from the lateral border of the tongue in a 63 year old man demonstrates the histopathology seen below. What is the diagnosis? Select an answer: A. Epithelial dysplasia B. Granular cell tumor C. Mucoepidermoid carcinoma D. Squamous cell carcinoma To sign up for our biweekly…
3 March 2023: Weekly Roundup #114
Here’s what you need to know about PathologyOutlines.com this week: 1. Worldwide Directory of Pathologists Our Directory profiles now have links for the institutions and subspecialties selected. For example, our Editor-in-Chief Dr. Raul Gonzalez has links on his profile for Emory University and GI / liver that show all other pathologists in the Directory who are…
2 March 2023: Textbook Updates
We have posted updates of the following topics: Bone marrow neoplastic > Bone marrow – neoplastic myeloid > AML not otherwise specified > AMML by Ramya Gadde, M.D., Rose Beck, M.D., Ph.D. Topic summary: As per the current 5th edition of WHO classification (2022), acute myelomonocytic leukemia (AMML) is a distinct entity within acute myeloid…
27 February 2023: Textbook Updates
We have posted updates of the following topics: CNS nontumor > Vascular disorders > Cerebral amyloid angiopathy by Nicolas Kostelecky, M.D., Jared T. Ahrendsen, M.D., Ph.D. Topic summary: Vasculopathy characterized by the accumulation of beta amyloid protein within small to medium sized blood vessels of the brain and leptomeninges; renders affected blood vessels fragile, leading…
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