Blog Feed

12 November 2024: Image Quiz #147

Authors: Jonathan C. Slack, M.D., Laura Warmke, M.D. A 17 year old boy has had a red, warm, pulsatile soft tissue mass on his forehead since birth. The lesion has recently enlarged and its histology is shown in the image below. What is the diagnosis? Select an answer: A. Arteriovenous malformation B. Congenital hemangioma C. Pyogenic granuloma D.…

11 November 2024: Textbook Updates

We have posted updates of the following topics: Kidney tumor > Non-renal cell tumors > Well differentiated neuroendocrine tumor (carcinoid) by Lin Cheng, M.D., Ph.D., Maria Tretiakova, M.D., Ph.D. Topic summary: Well differentiated epithelial neoplasm that arises from renal parenchyma and shows neuroendocrine differentiation. Rare tumor, associated with horseshoe kidney and mature teratoma of kidney.…

4 November 2024: Textbook Updates

We have posted updates of the following topics: Bone & joints > Other chondrogenic tumors > Bizarre parosteal osteochondromatous proliferation by Adeyinka O. Akinsanya, M.B.B.S., Laura Warmke, M.D. Topic summary: Benign, surface based lesion of bone frequently involving the small bones of the hands and feet; consists of an admixture of bland spindle cells, disorganized…

31 October 2024: Textbook Updates

We have posted updates of the following topics: Bladder & urothelial tract > Cytology > Cytology-general, normal findings & biomarker testing by Benjamin Luigi Petrykowski, D.O., Maria Luisa C. Policarpio-Nicolas, M.D., Maria Cecilia D. Reyes, M.D. Topic summary: The Paris system (TPS) is a standardized international reporting system for urinary cytology specimens; ancillary biomarker testing…

29 October 2024: Image Quiz #146

Authors: Alex McGeough, M.D., Divya Sharma, M.D. What histologic feature shown in the tumor image below best supports a diagnosis of squamous cell carcinoma? Select an answer: A. Generous eosinophilic cytoplasm B. Intercellular bridges C. Lack of glandular structures D. Presence of nucleoli To sign up for our biweekly image quiz e-newsletters and more, visit pathologyoutlines.com/subscribe.html.

28 October 2024: Textbook Updates

We have posted updates of the following topics: Breast > Other nonneoplastic > Cystic hypersecretory hyperplasia by Victoria M. Jones, M.D., Kristen E. Muller, D.O. Topic summary: Cystic hypersecretory hyperplasia (CHH) is a type of breast lesion characterized by cystically dilated ducts lined by bland cuboidal or columnar epithelium, filled with homogenous eosinophilic secretions that…

24 October 2024: Textbook Updates

We have posted updates of the following topics: Breast > Therapy > Immunotherapy by Ellen Yang, M.B.B.S., Hannah Y. Wen, M.D., Ph.D. Topic summary: Immunotherapy is the treatment that harnesses the body’s immune system to fight disease, particularly cancer; there are several types of immunotherapy, such as immune checkpoint inhibitor (ICI). Immune checkpoint inhibitors (ICI)…

23 October 2024: Case of the Month #543

Thanks to Dr. Vidya Arole and Dr. Wei Chen, Ohio State University Wexner Medical Center, Columbus, Ohio, USA for contributing this case and discussion and to Dr. Claudio Luchini, University and Hospital Trust of Verona, Verona, Italy for reviewing the discussion. Clinical history: A 70 year old man underwent an upper endoscopic ultrasound (EUS) for evaluation of a pancreatic…

21 October 2024: Textbook Updates

We have posted updates of the following topics: Kidney tumor > Childhood tumors > Anaplastic sarcoma of the kidney by Maria Laura Galluzzo Mutti, M.D., Gordan M. Vujanic, M.D., Ph.D. Topic summary: Anaplastic sarcoma of the kidney is a polyphenotypic sarcoma associated with DICER1 mutations. Histologically characterized by sheets of spindle cells and undifferentiated morphology,…

18 October 2024: Weekly Roundup #154

Here’s what you need to know about PathologyOutlines.com this week: 1. CAP 2024 Meeting The PathologyOutlines.com team, including founder and CEO Dr. Nat Pernick, will be attending the CAP 2024 meeting this weekend, October 20 – 21. Make sure to stop by our booth (#520), chat with our staff and grab some giveaways! 2. Directory…

17 October 2024: Textbook Updates

We have posted updates of the following topics: Chemistry, toxicology & urinalysis > Serology > Syphilis by Rongrong Huang, Ph.D. Topic summary: Serologic testing plays an essential role in syphilis evaluation, including clinical screening, disease diagnosis and staging and monitoring treatment response. There are 2 types of serologic testing for syphilis: treponemal tests detecting T.…

15 October 2024: Image Quiz #145

Authors: Priyadharshini Sivasubramaniam, M.B.B.S., Julie M. Jorns, M.D. In the setting of metastatic carcinoma to the bone, positive mammaglobin A immunohistochemistry is most suggestive of which primary site of origin? Select an answer: A. Breast B. Cervix C. Lung D. Ovary To sign up for our biweekly image quiz e-newsletters and more, visit pathologyoutlines.com/subscribe.html.

11 October 2024: Weekly Roundup #153

Here’s what you need to know about PathologyOutlines.com this week: 1. 2024 Q2 Directory Report The Q2 report for our Worldwide Directory of Pathologists is available to read at pathologyoutlines.com/directoryreport2024q2.html. It provides information not available elsewhere, including pathologist totals by U.S. state and Canadian province, subspecialty totals, the largest pathology institutions and the most popular pathologist profiles. We…

10 October 2024: Textbook Updates

We have posted updates of the following topics: CNS & pituitary tumors > Gliomas, glioneuronal tumors and neuronal tumors > Neuronal and mixed neuronal-glial tumors > Multinodular and vacuolating neuronal tumor (MVNT) by Antonio d’Amati, M.D., Francesca Gianno, M.D., Ph.D., Manila Antonelli, M.D., Ph.D. Topic summary: Neuronal tumor composed of multiple nodules of monomorphic neurons,…

7 October 2024: Textbook Updates

We have posted updates of the following topics: Gallbladder & extrahepatic bile ducts > Gallbladder nonneoplastic > Papillary hyperplasia by Nicholas L. Kolch, B.S., Kimberley J. Evason, M.D., Ph.D. Topic summary: Benign nonneoplastic change in gallbladder epithelium; may be primary in cause or secondary to anatomical malformations (pancreaticobiliary maljunction) and inflammatory diseases (including cholecystitis, cholelithiasis).…

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