14 June 2022: Image Quiz #84

Authors: Ameya Patil, M.D., M.S.Lizhi Zhang, M.D.

Which cell type (marked by an arrow) is considered abnormal if present in the left side of the colon?

Select an answer:

A. Enteroendocrine cells

B. Epithelial cells

C. Goblet cells

D. Paneth cells

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23 June 2021: Pathology Images of the Week

Here is a selection of new images from our free, online textbook:

Informatics, digital & computational pathology > Data representation and communication standards

The PNG image has been encoded into JPG using a high quality setting (approximately 329 KB).

Contributed by Chris Williams, M.D.

Uterus > Low grade endometrial stromal sarcoma

Deceptively well circumscribed tumor with a tan-yellow soft cut surface; microscopic evaluation revealed myometrial and lymphovascular invasion.

Contributed by Elizabeth Kertowidjojo, M.D., Ph.D., M.P.H.

Colon > Ulcerative colitis

Active chronic colitis with cryptitis is noted.

Contributed by Rachel Horton, D.O. and Catherine E. Hagen, M.D.

Liver & intrahepatic bile ducts > Histology

Periodic acid-Schiff with diastase (PASD) highlights the basement membrane of bile ducts. It also stains alpha-1 antitrypsin globules in hepatocytes in the setting of alpha-1 antitrypsin deficiency. The lack of globules in this image is a normal finding.

Contributed by Kimberley J. Evason, M.D., Ph.D.

Ovary > Yolk sac tumor

Schiller-Duval body

Contributed by Sharon Song, M.D.

24 February 2021: Images of the Week

Here is a selection of new images from our free, online textbook:

Colon > Ischemic colitis

Low power image showing crypt injury, marked crypt dropout, lamina propria hyalinization and vascular congestion.

Contributed by Gagandeep Kaur, M.D. and Monika Vyas, M.D.

Lymphoma & related disorders > Richter syndrome

H&E of Richter syndrome, diffuse large B cell lymphoma type. Diffuse sheets of large, atypical cells with finely dispersed chromatin and prominent nuclei.

Contributed by Shahbaz Khan, M.D.

Skin nontumor > Psoriasis

Higher magnification of subcorneal pustule in pustular psoriasis with elongated and dilated capillaries in the papillary dermis. Punch biopsy from the trunk (40x).

Contributed by Viktoryia Kazlouskaya, M.D., Ph.D.

Skin melanocytic tumor > Desmoplastic melanoma

Pure type desmoplastic melanoma consisting entirely of spindle cells in a fibrous stroma without convention melanoma (100x).

Contributed by Gregory A. Hosler, M.D., Ph.D.

Stains & molecular markers > ATM

ATM immunostaining of rectal adenocarcinoma.

Contributed by Joo-Shik Shin, M.B.B.S., Ph.D.

How can you search the textbook?

For desktop / tablet, you can either use the Google search bar in the upper right corner or visit PathologyOutlines.com and then scroll down to where the 60 chapters are listed, as demonstrated below.

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For any device you can use your favorite browser and type in PathologyOutlines.com in addition to the search term.

28 August 2020: Weekly Roundup #22

Here’s what’s new on PathologyOutlines.com this week:

1. Chapter Mergers

We have now merged the Lung nontumor and tumor chapters into a single Lung chapter. Other recent chapter mergers include Colon, Liver and Breast.

2. Promotional Email Contest Winner #2

Christina Arnold, who works at the University of Colorado in Denver, has won the second PathologyOutlines.com Promotional Email Contest! For simply opening up PathologyOutlines.com email blasts, Christina has won a $50 Amazon gift card.

If you’d like a chance at winning, click here for sign up information and terms.

3. COVID-19 Library 

Visit our COVID-19 Library and its News section to stay up to date on what pathologists need to know.

4. COVID-19 Diagnostic Test

The FDA has issued an emergency use authorization for the SalivaDirect COVID-19 diagnostic test, developed by the Yale School of Public Health (ASH Clinical News, posted 21 August 2020). See also Yale Medicine.