- Premalignant states for glioblastoma or Hodgkin lymphoma: We welcome your proposal to identify premalignant states for glioblastoma multiforme or Hodgkin lymphoma based on molecular and not histologic patterns. As described at Arch Pathol Lab Med 2018;142:558, complexity theory suggests that these states likely exist, even if there is no histologic evidence.
- Efficacy of large combinations of therapies to substantially reduce cancer deaths for aggressive lung, colon, pancreatic or breast malignancies, targeting different aspects of tumor cells, microenvironmental features (vasculature, stroma, extracellular matrix and inflammation) and systemic features (chronic inflammation, immune system dysfunction, hormonal activity, germline changes) (see Strategic plan to reduce cancer deaths).
- Better understanding of and possibly treatment for physiologic changes associated with cancer deaths shortly after diagnosis (see How cancer kills).
- Strategies to markedly improve cancer prevention behavior, such as implementing the American Code Against Cancer or other substantial changes to health related behavior.
Requirements: Proposal should be up to 500 words and include CVs of principal investigators. The deadline to apply is 30 September 2022.
See pathologyoutlines.com/ccngrants.html for more information.
Email Dr. Pernick at Nat@PathologyOutlines.com to apply.