28 April 2023: Weekly Roundup #120

Here’s what you need to know about PathologyOutlines.com this week:

1. Worldwide Directory of Pathologists Image Contest

This is your last chance to vote for your favorite Directory image by April 30th! Watch this video to learn more about the contest and vote here: surveymonkey.com/r/favorite_image

2. New Deputy Editor-in-Chief for GI Pathology

We are pleased to announce the appointment of Aaron R. Huber, D.O. as our new Deputy Editor-in-Chief for Gastrointestinal Pathology. Dr. Huber completed his D.O. degree at the University of Health Sciences-College of Osteopathic Medicine in Kansas City, Missouri. He completed his residency in anatomic and clinical pathology at the Naval Medical Center San Diego in San Diego, California and his fellowship in gastrointestinal and hepatobiliary pathology at the University of Rochester Medical Center in Rochester, New York. He is currently the Director of the Surgical Pathology Unit and Co-Director of the Gastrointestinal and Hepatobiliary Pathology Fellowship at the University of Rochester Medical Center.

3. New Informatics Topic

We are currently working on strengthening our Informatics, digital & computational pathology chapter. Check out our new topic on Automated assessment of cytology specimens by Drs. Joshua Levy and Louis Vaickus.

4. New Podcast

Dr. Pernick was recently featured in a podcast with Aleksandra Zuraw, D.V.M., Ph.D. of Digital Pathology Place. Listen at https://bit.ly/PathologyOutlinesComInc or watch here:

7 April 2023: Weekly Roundup #117

Here’s what you need to know about PathologyOutlines.com this week:

1. Worldwide Directory of Pathologists Image Contest

Vote for your favorite Directory image by April 30th! Watch this video to learn more about the contest and vote here: surveymonkey.com/r/favorite_image

2. Informatics

We are currently working on strengthening our Informatics, digital & computational pathology chapter. Check out our revised topic on Natural language processing by Drs. David Nai and Jerome Cheng.

3. The Pathology Job Market Post-COVID: Where are We Now?

Dr. Debra L. Zynger (our prior Editor-in-Chief) and Dr. Nat Pernick presented a poster at USCAP, “The Pathology Job Market Post-COVID: Where are We Now?” A PDF version of the poster, along with other related links, are listed at the top of our jobs page.

24 February 2023: Weekly Roundup #113

Here’s what you need to know about PathologyOutlines.com this week:

1. New Editorial Board Appointments

Dr. Kimberley Evason was recently appointed to our Editorial Board for Gastrointestinal Pathology. Dr. Evason is a physician-scientist and Associate Professor of Pathology at the University of Utah. She obtained her M.D. and Ph.D. through the Medical Scientist Training Program at Washington University in St. Louis. She then completed her Anatomic Pathology residency, fellowship in Gastrointestinal and Liver Pathology, and postdoctoral research training at University of California, San Francisco.

Dr. Jared Ahrendsen was recently appointed to our Editorial Board for Neuropathology. Dr. Ahrendsen is an Assistant Professor of Pathology of Neuropathology at Northwestern University Feinberg School of Medicine in Chciago. He earned his M.D. and Ph.D. from the University of Colorado Anschutz Medical Campus. He then completed a combined Anatomic Pathology / Neuropathology residency and fellowship at Beth Israel Deaconess Medical Center, Harvard Medical School in Boston, where he also served as Chief Resident. He also completed a fellowship in Forensic Pathology at the Oklahoma Office of the Chief Medical Examiner. His research interests include molecular diagnostics of brain tumors, trauma related neuropathology and the utilization of postmortem tissue to better understand human neurologic disease.

2. Informatics

Learn about Informatics, digital & computational pathology at pathologyoutlines.com/informatics.html. Make sure to read our topic on Computational pathology fundamentals & applications, written by Yomna Amer, M.B.B.Ch. and Anil Parwani, M.D., Ph.D., M.B.A.

3. Potential PathologyOutlines.com App

We are considering setting up a free mobile app. It would resemble what is currently available when using the website on mobile but, at least initially, the topics would be limited to the most important sections and we would try to improve formatting. Email Nat@PathologyOutlines.com with any suggestions.

For mobile use of the website, there is no option to convert to the standard home page, header and footer. Our decision to have mobile pages conform to the screen size apparently eliminated that option. We have added more links to the “Other links” tab on our homepage so you should be able to access all important pages.

27 January 2023: Weekly Roundup #110

Here’s what you need to know about PathologyOutlines.com this week:

1. Informatics

Learn about Informatics, digital & computational pathology at pathologyoutlines.com/informatics.html. View our Spectral imaging topic, recently written by Aisha Abdelhafez, M.Sc. and Anil Parwani, M.D., Ph.D., M.B.A.

2. Top Topics of 2022

11 of our topics reached more than 100,000 views in 2022, a new record:

1. Basal cell carcinoma (143,028 views)
2. Endometrioid carcinoma (132,439)
3. Fibroadenoma (119,546)
4. Pleomorphic adenoma (112,332)
5. Leiomyoma-general (108,854)
6. Dermatofibroma (cutaneous fibrous histiocytoma) (108,488)
7. Meningioma (106,805)
8. Neurofibroma-general (104,319)
9. Invasive urothelial carcinoma (101,073)
10. Clear cell renal cell carcinoma (100,269)
11. Schwannoma (100,175)

3. Top Countries

We now have posted visits by country in 2022 on our Statistics page. The top 10 countries by traffic are as follows:

1. United States (1,463,246 users)
2. Indonesia (795,776)
3. India (605,835)
4. United Kingdom (194,434)
5. Philippines (159,044)
6. Canada (116,659)
7. Nepal (109,367)
8. Australia (104,195)
9. Mexico (96,286)
10. Germany (95,852)

4. PubMed Links

We are making a small change to PubMed links. Currently, some are blue and others are green. While green links were for journal articles that were free full text for everyone, it turns out that this changes over time. Going forward, all new links created will be blue.

23 August 2022: Image Quiz #89

Authors: Ruhani Sardana, M.B.B.S., Anil Parwani, M.D., Ph.D., M.B.A.

Which technique is shown in the image below?

Select an answer:

A. Electron microscopy

B. Enzyme linked immunosorbent assay

C. Fluorescent in situ hybridization

D. Immunofluorescence

See the answer

To sign up for our biweekly image quiz newsletters and more, visit pathologyoutlines.com/subscribe.html.

23 June 2021: Pathology Images of the Week

Here is a selection of new images from our free, online textbook:

Informatics, digital & computational pathology > Data representation and communication standards

The PNG image has been encoded into JPG using a high quality setting (approximately 329 KB).

Contributed by Chris Williams, M.D.

Uterus > Low grade endometrial stromal sarcoma

Deceptively well circumscribed tumor with a tan-yellow soft cut surface; microscopic evaluation revealed myometrial and lymphovascular invasion.

Contributed by Elizabeth Kertowidjojo, M.D., Ph.D., M.P.H.

Colon > Ulcerative colitis

Active chronic colitis with cryptitis is noted.

Contributed by Rachel Horton, D.O. and Catherine E. Hagen, M.D.

Liver & intrahepatic bile ducts > Histology

Periodic acid-Schiff with diastase (PASD) highlights the basement membrane of bile ducts. It also stains alpha-1 antitrypsin globules in hepatocytes in the setting of alpha-1 antitrypsin deficiency. The lack of globules in this image is a normal finding.

Contributed by Kimberley J. Evason, M.D., Ph.D.

Ovary > Yolk sac tumor

Schiller-Duval body

Contributed by Sharon Song, M.D.

16 June 2021: Pathology Images of the Week

Here is a selection of new images from our free, online textbook:

Laboratory Administration & Management of Pathology Practices > Lean workflow / Six Sigma

An organized workspace with a space for all needed tools or materials for jobs done at the station readily allows one to identify when something is missing or out of place.

Contributed by Stephen J. Hardy, M.B.A.

Liver & intrahepatic bile ducts > Ductular reaction

The ductular profiles with complete and incomplete lumina at the portal – parenchymal interface are highlighted by CK19.

Contributed by Shahbaz Khan, M.D.

Skin nonmelanocytic tumor > Juvenile xanthogranuloma

Right leg, excision, juvenile xanthogranuloma, scattered Touton giant cells.

Contributed by Lamiaa Hamie, M.D., M.Sc. and Ossama Abbas, M.D.

Bladder, ureter & renal pelvis > Noninvasive papillary urothelial carcinoma high grade

High power showing architectural disorder, loss of polarity and nuclear pleomorphism in high grade papillary carcinoma.

Contributed by Michelle R. Downes, M.D.

Informatics, digital & computational pathology > Fluorescent microscopy applications

Interphase FISH showing translocation involving the EWSR1 gene at 22q12.

Contributed by Ruhani Sardana, M.B.B.S. and Anil Parwani, M.D., Ph.D., M.B.A.

2 December 2020: Images of the Week

Here are just a few of this week’s new images from our free, online textbook:

Low grade intraosseous (central) osteosarcoma

Cellular fascicles of spindle cells with mild nuclear atypia in a fibrosclerotic stroma.

Contributed by Borislav A. Alexiev, M.D.

AML with inv(3)(q21.3;q26.2) or t(3;3)(q21.3;q26.2)

Bone marrow aspirate showing a hypolobated megakaryocyte, increased blasts and a pseudo-Pelger-Hüet neutrophil.

Contributed by Alexa J. Siddon, M.D.

Telecytology

Snapshot of dynamic microscopy from the pathologist end (10x objective), showing annotations and the control buttons.

Contributed by Jason A. Thomas, C.T. and Sigfred Lajara, M.D.

Liver & intrahepatic bile ducts → Viral hepatitis → COVID-19

Occasional cases (15%) have sinusoidal microthrombi (600x).

Contributed by Stephen M. Lagana, M.D.

How can you search the textbook?

For desktop / tablet, you can either use the Google search bar in the upper right corner or visit PathologyOutlines.com and then scroll down to where the 61 chapters are listed, as demonstrated below.

For mobile, visit PathologyOutlines.com, click on “Chapters by Subspecialty” (as demonstrated below) and then click on the subspecialty, chapter and topic.

For any device you can use your favorite browser and type in PathologyOutlines.com in addition to the search term.