Author: Bin Xu, M.D., Ph.D.
A 45 year old man presents with a nasal cavity mass. A representative H&E of the mass is shown in the picture. Which of the following statements is true?
Select an answer:
A. Differential diagnoses include adenoid cystic carcinoma of salivary gland origin and HPV related multiphenotypic sinonasal carcinoma
B. Tumor is consistently negative for myoepithelial markers, e.g. SMA, calponin and S100
C. Tumor may be positive for EBV
D. 80% are positive for EWSR1 fusion
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