26 April 2022: Image Quiz #81

Author: Molly Housley Smith, D.M.D.

Oral examination of a patient reveals an asymmetric 4 mm red nodule at the dorsal tongue base. The patient is asymptomatic and was unaware of the finding. Biopsy of the lesion is shown. Which of the following is true regarding the diagnosis?

Select an answer:

A. Diagnosis of this entity relies heavily on immunohistochemical findings

B. Diagnosis represents reactive hyperplasia of a normal structure

C. Significant clinical follow up is recommended, since malignant transformation occurs in the majority of patients with this finding

D. This entity is more commonly found in older adults

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2 February 2022: Best Authors of 2021

Congratulations to the winners of the PathologyOutlines.com 2021 Best Author Award! This was a very competitive award and we greatly appreciate the contributions of those named below in addition to those of our other diligent authors in 2021, all of whom you can view here. You can view the winners from past years here.

Here are the 2021 winners:

  1. Oral cavity & oropharynx > Oropharynx squamous cell carcinoma > HPV negative: Written by Katherine Hulme, M.B.Ch.B. and Ruta Gupta, M.D. 
  2. Uterus > Stromal tumors > Low grade endometrial stromal sarcoma: Written by Elizabeth Kertowidjojo, M.D., Ph.D., M.P.H. and Lora Hedrick Ellenson, M.D. 
  3. Breast > Papillary carcinoma > Solid papillary carcinoma: Written by Sofia Lérias, M.D. and Melinda Lerwill, M.D. 
  4. CNS tumor > Other tumors > Hemangioblastoma: Written by Rebecca Yoda, M.D. and P.J. Cimino, M.D., Ph.D. 
  5. Liver > Other malignancies > Hepatoblastoma: Written by Rui Caetano Oliveira, M.D. and Maria Augusta Cipriano, M.D. 

If you are interested in being an author for PathologyOutlines.com, please send your CV and a list of topics or chapters you are interested in writing / reviewing to our author coordinators at Authors@PathologyOutlines.com. You may also review your qualifications here.

21 July 2021: Pathology Images of the Week

Here is a selection of new images from our free, online textbook:

Oral cavity & oropharynx > Lingual tonsil

The posterior lateral tongue contains 6 – 8 larger red papules.

Contributed by Molly Housley Smith, D.M.D.

Ovary > Corpus luteum cyst

Intermediate magnification showing bilayered cyst lining with inner granulosa cells (lower part of the image) and outer layer of theca cells (upper part of the image).

Contributed by Aurelia Busca, M.D., Ph.D.

Stains & CD markers > WT1

The tumor cells show strong nuclear positivity for WT1. The necrotic tumor cells lose antigenicity for WT1. The final diagnosis is WT1 positive malignant mesothelioma.

Contributed by Urooba Nadeem, M.D. and Aliya N. Husain, M.D.

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