23 August 2022: Image Quiz #89

Authors: Ruhani Sardana, M.B.B.S.Anil Parwani, M.D., Ph.D., M.B.A.

Which technique is shown in the image below?

Select an answer:

A. Electron microscopy

B. Enzyme linked immunosorbent assay

C. Fluorescent in situ hybridization

D. Immunofluorescence

To sign up for our biweekly image quiz newsletters and more, visit pathologyoutlines.com/subscribe.html.

19 August 2022: Weekly Roundup #96

Here’s what you need to know about PathologyOutlines.com this week:

1. Anniversary Updates

PathologyOutlines.com is now starting its 22nd year. This year, we plan to accelerate our topic updates, add more Board Review style question features, expand our Worldwide Directory of Pathologists and have more What’s New in Pathology newsletters. Email Dr. Pernick your suggestions on how we can better help pathologists at Nat@PathologyOutlines.com.

2. Author Recruitment

We invite pathologists to write for our textbook, although either they or someone on their author team must have expertise in the topic they are writing about. The most difficult author qualification is usually: “Within the past 15 years, you must have published at least 5 first or last author journal articles other than case reports, in U.S., European or comparable journals, verifiable on PubMed, about the subspecialty in which you want to write.” See pathologyoutlines.com/authorinformation.html for more information or email Dr. Pernick at Nat@PathologyOutlines.com if interested.

3. Image Contest

Do you have great pathology images? We will soon start a contest to choose the best pathology images, which will be selected from images that pathologists have posted in their Directory profile. We are holding this contest because pathologists love images and because we want to publicize the Directory as a great way to learn about pathologists worldwide.

To participate, you have to create a (free) Directory profile at pathologyoutlines.com/directorysignup.html and add a high quality pathology image. While we are still working out the details, there will likely be prizes of $250, $150 and $100 for the winners. Our Editorial Board or others will screen the images and select the top 20. More details will follow.

Email Nat@PathologyOutlines.com with any ideas on how to make the contest more efficient.

17 August 2022: Case of the Month #518

Thanks to Drs. Mariel Molina Nunez and Julie Jorns, Medical College of Wisconsin, Milwaukee, Wisconsin, USA, for contributing this case and discussion and to Dr. Kristen Muller, Dartmouth Geisel School of Medicine, Lebanon, New Hampshire, USA for reviewing the discussion.

Clinical history:

A postmenopausal woman, on a screening mammogram, was found to have a 15 mm mass in the lower inner quadrant of the left breast. Breast ultrasound revealed a 1.7 cm complex solid and cystic mass.

All cases are archived on our website. To view them sorted by case number, diagnosis or category, visit our main Case of the Month page.

To subscribe to Case of the Month or our other email newsletters, visit pathologyoutlines.com/subscribe.html.

12 August 2022: Weekly Roundup #95

Here’s what you need to know about PathologyOutlines.com this week:

1. Curing Cancer Network

We have posted our monthly Curing Cancer Network (CCN) newsletter for July at https://conta.cc/3PV49T4. To receive CCN updates directly to your inbox, visit https://lp.constantcontactpages.com/su/onz6IND.

2. Advertising

Please use Ads@PathologyOutlines.com to contact us for all possible advertisements, including Jobs, Fellowships, Conferences, banners, books, CME and e-blasts. This email address is monitored by several people. Using other email addresses may cause a delayed response.

3. Informatics

Are you interested in informatics? We have significantly improved our Informatics and Digital Pathology chapter and welcome your suggestions for new topics of interest to pathologists.

4. Caching

To improve loading speed, most of our pages are cached for 4 hours. This means that they do not change for you (even if we change the page) until 4 hours has elapsed after any change. If you load the page on another device that has not previously loaded the page, you will get the most recent version. After the 4 hours has expired, the current version of the page will load.

Note that your institution may also have its own caching policies. For example, one institution kept the same copy of the Jobs page cached for 24 hours so new job ads would not be seen until the next day. Obviously, that is beyond our control.

For any comments or questions about caching or topic suggestions, email Comments@PathologyOutlines.com.

9 August 2022: Image Quiz #88

Authors: Zena Jameel, M.D.Marilin Rosa, M.D.

Which of the following is a relevant feature of invasive papillary carcinoma of the breast?

Select an answer:

A. Commonly encountered breast tumor

B. Graded according to nuclear size

C. May mimic metastases from other organs

D. Myoepithelial cells at the periphery

E. Positive for Napsin A and PAX8

To sign up for our biweekly image quiz newsletters and more, visit pathologyoutlines.com/subscribe.html.

5 August 2022: Use of Author Contributed Images

We appreciate all the authors who have contributed images to topics at PathologyOutlines.com. In general, these images are protected by our copyright and cannot be used by others (except for the contributors) without our consent. However, they typically can be used for limited educational purposes under the Fair Use doctrine without consent (see https://libguides.unm.edu/images/fairuse).

Recently, several organizations, both nonprofits and businesses, have requested permission to use some of our images. We may allow this after review, but typically we require that they attribute the image to the submitter and to us. For business use, if a large number of images are requested, we charge the business a fee solely to cover our administrative costs (i.e., we do not pay the author).

If you have any questions about using our images, please email comments@pathologyoutlines.com.

2 August 2022: Worldwide Directory of Pathologists Update

We have now created a list of all pathologists at academic institutions in the U.S. and Canada for entry into the Directory. We currently have 7,000+ U.S. profiles, 750+ Canadian profiles (mostly academic) and we estimate that U.S. and Canadian academic pathologists will total ~10,000 when all profiles are created, targeted for October 2022.

Pathologists are defined for the Directory as having a doctoral degree plus pathology residency or fellowship training (or comparable); this includes PhDs and other subspecialists. Typically, they perform or can perform direct patient care at the level of an AP or CP attending. We include residents and fellows in the Directory, but not medical students.

We also include pathologists who are now doing something else as well as deceased pathologists already in the Directory for 5 years after passing. We are able to inactivate Directory entries if a pathologist requests for their profile to be removed.

See the blue box on the Directory page to learn how to add or update your profile. We plan to add a Consultation search in the fall of 2022, so you may want to review your profile to make sure it is as accurate as possible.

26 July 2022: Image Quiz #87

Authors: Christopher Dall, M.D.Debra L. Zynger, M.D.

Teratoma with somatic type malignancy most commonly contains which histologic type?

Select an answer:

A. Adenocarcinoma

B. Primitive neuroectodermal tumor

C. Rhabdomyosarcoma

D. Sarcoma, not otherwise specified

E. Squamous cell carcinoma

To sign up for our biweekly image quiz newsletters and more, visit pathologyoutlines.com/subscribe.html.

22 July 2022: Weekly Roundup #94

What’s new on PathologyOutlines.com this week?

1. Tip of the Month – July 2022

We have posted a YouTube video highlighting the July 2022 PathologyOutlines.com Tip of the Month. View it at https://youtu.be/O3dMN4QqoGU.

2. Author Recruitment

We continue to look for academics who meet our author qualifications. If interested, email Nat@PathologyOutlines.com with your CV and areas of interest.

3. Senior Authors

We have removed the position of Senior Author from our topics, which we have not used for several years. Although at least 1 member of the author team must meet our author qualifications, we are no longer making a distinction on the website between the authors.

4. Tracking / Cookies

We are investigating the use of tracking software that does not collect any information about you (i.e., no cookies). While we do have to track basic statistics (page views, visits, clicks) in order to function, we want to maintain your privacy and keep the site as user friendly as possible. We will keep you advised.

20 July 2022: Case of the Month #517

Thanks to Dr. Viktoryia Kazlouskaya, University of Pittsburgh, Pittsburgh, Pennsylvania, USA, for contributing this case and discussion and to Dr. Jonathan Ho, University of the West Indies, Mona, Jamaica for reviewing the discussion.

Clinical history:

A man in his 50s presented with leonine (resembling a lion) facies and keratotic papules all over his body. He mentioned that the condition has been present since he was a child and that his mother and siblings had similar skin features. A skin biopsy was obtained.

All cases are archived on our website. To view them sorted by case number, diagnosis or category, visit our main Case of the Month page.

To subscribe to Case of the Month or our other email newsletters, visit pathologyoutlines.com/subscribe.html.