3 February 2023: Weekly Roundup #111

Here’s what you need to know about PathologyOutlines.com this week:

1. USCAP 2023

Visit us next month at USCAP, Booth #112! We look forward to meeting you.

2. Mastodon Account / Social Media

Follow our PathologyOutlines.com account on Mastodon, a Twitter alternative, at med-mastodon.com/@pathout. The header on PathologyOutlines.com has icons for all of our social media accounts in the upper right corner, next to the Search box.

3. Curing Cancer Network: American Cancer Society – Updated Mission Statement

The American Cancer Society has updated its mission statement, which now reads as shown below:

“The mission of the American Cancer Society is to improve the lives of people with cancer and their families through advocacy, research, and patient support, to ensure everyone has an opportunity to prevent, detect, treat, and survive cancer.” See https://lnkd.in/gbKwWdS6.

The prior mission statement was “to save lives, celebrate lives, and lead the fight for a world without cancer.” 

While I don’t know the details regarding the change, I am pleased with this new, more rational mission statement that reflects that cancer is an inherent part of our biology that cannot be vanquished. I had previously criticized the phrase “world without cancer”:

“The human body is composed of a myriad of interacting networks positioned at critical states, which is required for network flexibility to enable embryonic development, the inflammatory response to trauma and infection and the capability for our species to evolve to a changing environment. However, the tradeoff for maintaining these critical states is that cancer, a type of catastrophic systemic failure, is inevitable. We can reduce its incidence, we can detect it earlier and we can treat it more effectively but attaining a “world without cancer” (American Cancer Society, accessed 13Nov20) is not possible.”

27 January 2023: Weekly Roundup #110

Here’s what you need to know about PathologyOutlines.com this week:

1. Informatics

Learn about Informatics, digital & computational pathology at pathologyoutlines.com/informatics.html. View our Spectral imaging topic, recently written by Aisha Abdelhafez, M.Sc. and Anil Parwani, M.D., Ph.D., M.B.A.

2. Top Topics of 2022

11 of our topics reached more than 100,000 views in 2022, a new record:

3. Top Countries

We now have posted visits by country in 2022 on our Statistics page. The top 10 countries by traffic are as follows:

  1. United States (1,463,246 users)
  2. Indonesia (795,776)
  3. India (605,835)
  4. United Kingdom (194,434)
  5. Philippines (159,044)
  6. Canada (116,659)
  7. Nepal (109,367)
  8. Australia (104,195)
  9. Mexico (96,286)
  10. Germany (95,852)

4. PubMed Links

We are making a small change to PubMed links. Currently, some are blue and others are green. While green links were for journal articles that were free full text for everyone, it turns out that this changes over time. Going forward, all new links created will be blue.

24 January 2023: Image Quiz #100

Authors: Akira Yoshikawa, M.D.Andrey Bychkov, M.D., Ph.D.

Which phase of diffuse alveolar damage (DAD) is most clearly demonstrated in this histological image?

Select an answer:

A. Active

B. Exudative (acute)

C. Fibrotic (chronic)

D. Postinflammatory

E. Proliferative / organizing (subacute)

To sign up for our biweekly image quiz e-newsletters and more, visit pathologyoutlines.com/subscribe.html.

20 January 2023: Weekly Roundup #109

Here’s what you need to know about PathologyOutlines.com this week:

1. Worldwide Directory of Pathologists Ambassadors

Do you want to promote the pathologists at your institution? If so, consider becoming a Directory Ambassador! As Ambassador, you help ensure that the Directory includes all practicing pathologists for your institution and otherwise assist in making the Directory as accurate as possible. Ambassadors can be residents, fellows, faculty or staff, can split the work with other ambassadors and don’t have to review all the pathologists at the same time. Ambassadors are not paid but are listed on this page, get a gift at the time of the annual USCAP meeting and are appreciated by pathologists at their institution for helping promote their work.

2. Curing Cancer Network: How Cancer Kills

We have updated our essay, How Cancer Kills. See an excerpt below:

“Our strategic plan aims to reduce U.S. cancer deaths from 600,000 (projected cancer deaths in 2022) to 100,000 per year. To reach this ambitious goal, we must better understand how cancer actually kills people. This essay proposes that cancer often kills indirectly by promoting marked physiologic disruptions in life’s essential networks; however, physicians can prevent these deaths by correcting the network changes even before the cancer itself is treated. In addition, advanced cancer kills by creating a sense of futility, which causes individuals and the medical system to give up the fight.”

3. Screening Colonoscopies

Dr. Pernick appeared on Channel 7 (Detroit) discussing how patients with private insurance or Medicare should not be charged for screening colonoscopies under the Affordable Care Act. Watch the video and read the article here. His blog about his experience is here.

4. Website Traffic

For 2022, PathologyOutlines.com averaged 54,904 sessions (visits) per day, an increase of 10.9% over 2021. New traffic records for 2022 include 20,039,946 total sessions, 6,151,434 users, 4,299,793 home page views and an incredible 45,164,115 total page views. Thanks for your support and suggestions to improve the website.

Currently, statistics are obtained using Google Analytics 3, which is changing to Google Analytics 4 in July 2023. Most statistics will be comparable but some may change based solely on the methodology.

18 January 2023: Case of the Month #523

Thanks to Dr. Raul Gonzalez, Emory University School of Medicine, Atlanta, Georgia, USA for contributing this case and discussion and to Dr. Aaron R. Huber, University of Rochester Medical Center, Rochester, New York, USA, for reviewing the discussion.

Clinical history:

A 25 year old man complaining of abdominal pain is found to have a 4 cm gastric mass, which is resected.

All cases are archived on our website. To view them sorted by case number, diagnosis or category, visit our main Case of the Month page.

To subscribe to Case of the Month or our other email newsletters, visit pathologyoutlines.com/subscribe.html.

13 January 2023: New Editorial Board Appointments

Several pathologists have recently been appointed or promoted to our Editorial Board. For a comprehensive list of our Editors, see our Editorial Board page.

Dr. Jonathan D. Ho has been promoted from the Editorial Board to our new Deputy Editor in Chief for Dermatopathology. Dr. Ho is Jamaican and completed his M.B.B.S. at The University of the West Indies, Mona Campus. After working as a dermatology registrar at the University Hospital of the West Indies in Kingston Jamaica, he completed specialist training in Dermatology and fellowship training in Dermatopathology in the International Graduate Training Program at Boston University School of Medicine. He is ICDP-UEMS board certified in Dermatopathology. He currently serves as the Co-director of the Dermatology residency program and the Director of Dermatopathology at The University of the West Indies, Mona Campus. His research interests include scarring and other disorders of fibrosis, complex medical dermatology and skin disease in richly pigmented skin. 

Dr. Josephine Dermawan has been appointed to our Editorial Board for Bone and Soft Tissue Pathology and Molecular Pathology. Dr. Dermawan is an Associate Staff at Cleveland Clinic Robert J. Tomsich Institute of Pathology and Laboratory Medicine. She completed her Anatomic and Clinical Pathology residency and Bone and Soft Tissue Pathology fellowship at Cleveland Clinic. She subsequently did a Molecular Genetic Pathology fellowship at Memorial Sloan Kettering Cancer Center.

Dr. Kyle Devins has been appointed to our Editorial Board for Gynecologic Pathology. Dr. Devins is an attending physician in the Department of Pathology at Massachusetts General Hospital and an Instructor of Pathology at Harvard Medical School. After obtaining his medical degree at SUNY Upstate Medical University, he completed residency training in Anatomic and Clinical Pathology at the Hospital of the University of Pennsylvania, followed by fellowships in Selective Surgical Pathology at Massachusetts General Hospital before joining the faculty in 2022. Dr. Devins provides diagnostic evaluation of gynecologic, genitourinary and breast specimens. His research seeks to improve the understanding and classification of ovarian, uterine and peritoneal neoplasia, particularly mesenchymal and sex cord-stromal tumors.

Dr. P.J. Cimino has been appointed to our Editorial Board for Neuropathology. He is a Pathologist-Scientist and Head of the Neuropathology Unit for the Surgical Neurology Branch in the National Institute for Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH). Dr. Cimino obtained his M.D. and Ph.D. in Neurobiology from the combined Medical Scientist Training Program (MSTP) at the University of Washington, Seattle. He then completed a combined Anatomic Pathology residency and Neuropathology fellowship training program at Washington University in St. Louis. Prior to joining the NIH, Dr. Cimino was an Assistant Professor on the Physician-Scientist track in the Department of Laboratory Medicine and Pathology at the University of Washington, Seattle.

11 January 2023: #PathOutPic Twitter Campaign

PathologyOutlines is publicizing the use of the Twitter hashtag #pathoutpic to identify possible histopathology images from Twitter to post in our online textbook. If you tweet high quality histopathology images and are willing to grant us permission to use these images on PathologyOutlines.com, please include the #pathoutpic hashtag in your tweet.

Every few weeks, our image representative will search Twitter for posts with this hashtag. The image representative will select the best images based on image quality (good focus, white balance, visually interesting, etc.), appropriate and reasonable associated text (i.e., the tweet) and whether the image is useful for the appropriate topic(s). This decision is solely within the discretion of the image representative. Not all images with the hashtag will be selected. We will only consider hashtags on the original tweets; users cannot give permission for images they do not own.

In general, images will be posted in the appropriate topic under a header that states “Contributed by @[username] on Twitter” with the diagnosis as the image caption and the Twitter post as the image legend. A URL link to the Twitter post will be included. We may also retweet the original posts with the selected image.

We give permission to the image owner to use the image in other publications, as long as this does not restrict the use of the image on our website. If users post an image with the hashtag but later wish to revoke permission for our site to post the image, they may contact us separately.

10 January 2023: Image Quiz #99

Author: Nick Baniak, M.D.

A 67 year old man presents with a solitary liver lesion. Glypican 3 staining was performed as part of a panel (see image below). What is the most likely diagnosis?

Select an answer:

A. Cirrhotic nodule

B. Focal nodular hyperplasia

C. Hepatic adenoma

D. Hepatocellular carcinoma

To sign up for our biweekly image quiz e-newsletters and more, visit pathologyoutlines.com/subscribe.html.

6 January 2023: Weekly Roundup #108

Happy New Year! Here’s what you need to know about PathologyOutlines.com this week:

1. Tip of the Month – December 2022

We have posted a YouTube video highlighting our blog features for the December 2022 edition of PathologyOutlines.com’s Tip of the Month. View it at https://youtu.be/WAJPS3yj94g.

2. Curing Cancer Network

We have posted our first essay to discuss details of our strategic plan to substantially reduce cancer deaths. Currently, cancer is the #2 cause of death in the United States after heart disease, causing about 600,000 deaths per year. This essay discusses cancer deaths in more detail. See pathologyoutlines.com/ccnblog/strategicplandiscussion.html for more information and click here to sign up for our Curing Cancer Network newsletter. You can also text CURINGCANCERNET (with no spaces) to 22828 to sign up.

3. Topic Updates

How can you determine the status of a topic that you think needs updating, whether it is written or pending? If the topic says “update in progress,” then it has been assigned. This may mean it has been “reserved” but the author is working on another topic first. We are trying to improve the turnaround times for topics, but let us know at comments@pathologyoutlines.com if you have any concerns about a particular topic.

4. New Address and Staff Update

We are moving to a smaller office in the next building later this month but are already starting to use our new mailing address of 30150 Telegraph Road, Suite 119, Bingham Farms, Michigan 48025.

We are also continuing to grow – our 24th staff member will start this month, and almost all staff members work remotely. Our team currently lives in 8 states (Michigan, Arizona, California, Florida, Nevada, New York, North Carolina and Oregon). Although there may be a benefit to having people in the office (more collaboration and exchange of ideas), most employees prefer to work from home and we don’t want to force them to drive to work.

27 December 2022: Image Quiz #98

Authors: Susan Prendeville, M.D.Bonnie Choy, M.D.

A 65 year old man underwent radical cystectomy for a bladder mass and the entire tumor looked like the histologic image shown below. Which of the following is true regarding this type of tumor arising in the urinary bladder?

Select an answer:

A. Gross examination usually shows a small tumor

B. Hematuria is not a clinical feature

C. It is associated with Schistosoma haematobium infection

D. It is the most common type of bladder carcinoma

E. Smoking is not a risk factor

To sign up for our biweekly image quiz e-newsletters and more, visit pathologyoutlines.com/subscribe.html.