19 May 2021: Pathology Images of the Week

Here is a selection of new images from our free, online textbook:

Lymphoma & related disorders > Large B cell lymphomas-special subtypes > EBV+

Low power view showing large transformed cells admixed with small lymphocytes.

Contributed by Sudhir Perincheri, M.B.B.S., Ph.D.

Lymphoma & related disorders > PTLD-polymorphic

400x magnification image demonstrating a polymorphic lymphoid infiltrate with full maturation, ranging from small, mature lymphoid cells to intermediate to large sized immunoblastic cells. Scattered plasma cells and eosinophils are also seen.

Contributed by Daniel Cassidy, M.D. and Jennifer Chapman, M.D.

Prostate gland & seminal vesicles > Adenosis / atypical adenomatous hyperplasia

Prostate, transurethral resection, adenosis. Medium power view of crowded, closely spaced acini lined by cells with clear cytoplasm and normal size nuclei (H&E, 20x).

Contributed by Cristina Magi-Galluzzi, M.D., Ph.D.

Salivary glands > Basal cell adenoma

Eosinophilic hyaline material is present in the tumor nest.

Contributed by Shuanzeng Wei, M.D., Ph.D.

Breast > Cytology

Ductal carcinoma in situ. Clusters of cytologic malignant cells with open chromatin (FNA, Pap stain, 20x).

Contributed by Areej M. Al Nemer, M.D.