9 June 2021: Pathology Images of the Week

Here is a selection of new images from our free, online textbook:

Salivary glands > Mucoepidermoid carcinoma

Solid areas of the tumor are formed by different proportions of epidermoid (squamous) cells (red arrow), mucus cells (green arrow) and intermediate cells (yellow arrow) (histopathology, H&E stain, 10x).

Contributed by Rema A. Rao, M.D. and Saeed Asiry, M.D.

Skin melanocytic tumor > Invasive melanoma

44 year old woman with 0.8 cm nodule on her back. Scanning magnification shows a nodular melanocytic proliferation with minimal junctional component (2x).

Contributed by Michele Donati, M.D.

Skin nonmelanocytic tumor > Keratoacanthoma

An endophytic squamous proliferation with central crater filled with keratin.

Contributed by Poonam Sharma, M.B.B.S.

Bladder, ureter & renal pelvis > Urothelial carcinoma – invasive > Nested

Anastomosing, irregular, large nested and inverted growth of cytologically bland urothelium with desmoplastic stromal reaction (4x).

Contributed by Megan L. Brown, M.D. and Maria Tretiakova, M.D., Ph.D.

Esophagus > Ectopic sebaceous glands

Mature sebaceous gland within the lamina propria.

Contributed by Yukihiro Nakanishi M.D., Ph.D.

24 February 2021: Images of the Week

Here is a selection of new images from our free, online textbook:

Colon > Ischemic colitis

Low power image showing crypt injury, marked crypt dropout, lamina propria hyalinization and vascular congestion.

Contributed by Gagandeep Kaur, M.D. and Monika Vyas, M.D.

Lymphoma & related disorders > Richter syndrome

H&E of Richter syndrome, diffuse large B cell lymphoma type. Diffuse sheets of large, atypical cells with finely dispersed chromatin and prominent nuclei.

Contributed by Shahbaz Khan, M.D.

Skin nontumor > Psoriasis

Higher magnification of subcorneal pustule in pustular psoriasis with elongated and dilated capillaries in the papillary dermis. Punch biopsy from the trunk (40x).

Contributed by Viktoryia Kazlouskaya, M.D., Ph.D.

Skin melanocytic tumor > Desmoplastic melanoma

Pure type desmoplastic melanoma consisting entirely of spindle cells in a fibrous stroma without convention melanoma (100x).

Contributed by Gregory A. Hosler, M.D., Ph.D.

Stains & molecular markers > ATM

ATM immunostaining of rectal adenocarcinoma.

Contributed by Joo-Shik Shin, M.B.B.S., Ph.D.


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