Authors: Matthew Franklin, M.D., Stephen Somach, M.D.
The photomicrograph shown below depicts an excision specimen from a carpenter presenting with a painful nodule of the right palm. What is the diagnosis?
Select an answer:
A. Epidermoid cyst
B. Foreign body granuloma
C. Osteoma cutis
D. Pilomatricoma
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Here is a selection of new images from our free, online textbook:
Noninvasive lepidic adenocarcinoma (left) juxtaposed with adjacent uninvolved lung parenchyma (right). The lepidic adenocarcinoma is characterized by thickened alveolar septa lined by atypical overlapping cuboidal cells.
Contributed by Jonathan Keow, M.D., Ph.D.
High power view of epithelial lining with maturation of squamous epithelium, which lacks a granular layer (trichilemmal differentiation).
Contributed by Aaron Muhlbauer, M.D. and Jodi Speiser, M.D.
Palisaded granuloma annulare. Arm of a 50 year old woman.
Contributed by Stephen Somach, M.D.
Leiomyosarcoma of the vulva, morphologically low grade, with moderately atypical, round to cigar shaped nuclei with focally prominent nucleoli (400x). Mitoses are rare (1 – 2 per 10 high power fields) and necrosis is absent.
Contributed by David B. Chapel, M.D.
A low power view shows papillary / verrucous epithelial hyperplasia with band-like plasma cell infiltrate in the scrotum.
Contributed by Liwei Jia, M.D., Ph.D.
Anterior cranial base fractures (yellow arrows).
Contributed by Lorenzo Gitto, M.D., Robert Stoppacher, M.D., Serenella Serinelli M.D., Ponni Arunkumar, M.D. and Luigi Bonaccorso, M.D.
Here is a selection of new images from our free, online textbook:
Trephine bone marrow biopsy showing an interstitial neoplastic infiltrate at high power, with moderate cytoplasm, irregular nuclear contours and prominent nucleoli.
Contributed by Siba El Hussein, M.D. and Joseph Khoury, M.D.
Low power magnification shows a lobulated soft tissue tumor with mixed fibrous and myxoid areas located within subcutaneous tissue.
Contributed by David Suster, M.D.
CIC-DUX4 fusion tumor (DUX4, 10x), involving soft tissue of flank.
Contributed by Bradford Siegele, M.D., J.D.
Superficial and deep perivascular and periadnexal lymphocytic infiltrate (H&E, 40x).
Contributed by Kiran Motaparthi, M.D.
Myxoid changes (gray-blue areas) are visible in the ganglion wall on the right. The remaining wall is composed of dense pink collagenous stroma. The lining of the wall does not show epithelial cells.
Contributed by Serenella Serinelli, M.D., Ph.D.
For desktop / tablet, you can either use the Google search bar in the upper right corner or visit PathologyOutlines.com and then scroll down to where the 60 chapters are listed, as demonstrated below.
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Here is a selection of new images from our free, online textbook:
Hyperkeratosis, papillomatosis, hypergranulosis, koilocytosis and inward bending of rete ridges at borders of lesion. Dermal papillae show dilated capillaries.
Contributed by Heba Ahmed Abdelkader, M.D.
Scanning magnification shows the dilated lymphatics in the submucosa of the small intestine (H&E, 2x).
Contributed by Haider A. Mejbel, M.D.
High power view of PGA showing small tubular glands with low cuboidal epithelium and bland nuclei.
Contributed by Supriya Srivastava M.D., Ph.D.
Nodular thyroid.
Contributed by Andrey Bychkov, M.D., Ph.D.
Anastomosing thin trabeculae of mildly atypical epithelioid and spindled cells within fibrous stroma.
Contributed by Borislav A. Alexiev, M.D.
For desktop / tablet, you can either use the Google search bar in the upper right corner or visit PathologyOutlines.com and then scroll down to where the 60 chapters are listed, as demonstrated below.
For mobile, visit PathologyOutlines.com, click on “Chapters by Subspecialty” (as demonstrated below) and then click on the subspecialty, chapter and topic.
For any device you can use your favorite browser and type in PathologyOutlines.com in addition to the search term.
Here is a selection of new images from our free, online textbook:
Low power image showing crypt injury, marked crypt dropout, lamina propria hyalinization and vascular congestion.
Contributed by Gagandeep Kaur, M.D. and Monika Vyas, M.D.
H&E of Richter syndrome, diffuse large B cell lymphoma type. Diffuse sheets of large, atypical cells with finely dispersed chromatin and prominent nuclei.
Contributed by Shahbaz Khan, M.D.
Higher magnification of subcorneal pustule in pustular psoriasis with elongated and dilated capillaries in the papillary dermis. Punch biopsy from the trunk (40x).
Contributed by Viktoryia Kazlouskaya, M.D., Ph.D.
Pure type desmoplastic melanoma consisting entirely of spindle cells in a fibrous stroma without convention melanoma (100x).
Contributed by Gregory A. Hosler, M.D., Ph.D.
ATM immunostaining of rectal adenocarcinoma.
Contributed by Joo-Shik Shin, M.B.B.S., Ph.D.
For desktop / tablet, you can either use the Google search bar in the upper right corner or visit PathologyOutlines.com and then scroll down to where the 60 chapters are listed, as demonstrated below.
For mobile, visit PathologyOutlines.com, click on “Chapters by Subspecialty” (as demonstrated below) and then click on the subspecialty, chapter and topic.
For any device you can use your favorite browser and type in PathologyOutlines.com in addition to the search term.
Here is a selection of new images from our free, online textbook:
Higher power image of the breast lumpectomy specimen demonstrates the dual cell population of myoepithelial cells surrounding epithelial glands with luminal secretions. Diagnosis: adenomyoepithelioma.
Contributed by Hannah Y. Wen, M.D., Ph.D.
Well circumscribed and nonencapsulated large mass with a red-brown color, focal honeycombed appearance, sponge-like consistency and foci of fibrosis.
Contributed by Lizhi Zhang, M.D.
Multicystic mesothelioma (top) involving the omentum (bottom). The lesion comprises multiple variably sized, predominantly collapsed cysts. It involves the omental surface without infiltration of underlying fat (H&E, whole slide).
Contributed by David B. Chapel, M.D.
In the superficial dermis, there are dilated thin walled vessels and prominent fibrosis overlying a polymorphous inflammatory infiltrate in this established lesion (H&E, 40x).
Contributed by Kiran Motaparthi, M.D.
Ossifying fibromyxoid tumor. Nodular growth of uniform, round or ovoid cells with bland nuclei.
Contributed by Borislav A. Alexiev, M.D.
For desktop / tablet, you can either use the Google search bar in the upper right corner or visit PathologyOutlines.com and then scroll down to where the 61 chapters are listed, as demonstrated below.
For mobile, visit PathologyOutlines.com, click on “Chapters by Subspecialty” (as demonstrated below) and then click on the subspecialty, chapter and topic.
For any device you can use your favorite browser and type in PathologyOutlines.com in addition to the search term.
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