7 April 2021: Images of the Week

Here is a selection of new images from our free, online textbook:

Cervix > HSIL / CIN II / CIN III

At high magnification, HSIL / CIN III lacks maturation (400x).

Contributed by Khaled J. Alkhateeb, M.B.B.S.

Ovary > Fibroma

Ovarian fibroma: the cut surface reveals a dense white mass within the ovary (left); outer surface of the fibroma is smooth and lightly vascularized (right).

Contributed by Rex Bentley, M.D.

Testis & epididymis > Adult granulosa cell

Low power view of numerous small uniform spaces (microfollicles) with hyalinized basement membrane material (Call-Exner bodies).

Contributed by Kristine M. Cornejo, M.D.

Microbiology & parasitology > Zygomycetes

Evaluation of fungal forms. H&E stained FFPE tissue showing broad pauciseptate ribbon-like hyphae in necrotic sinonasal tissue.

Contributed by Sixto M. Leal, Jr., M.D., Ph.D.

Skin nonmelanocytic tumor > Syringoma

Histologic sections showing cysts, nests and cords in a paisley or tadpole shaped pattern. No cytologic atypia or mitotic figures are seen (H&E, original magnification 100x).

Contributed by Aadil Ahmed, M.D. and Sara C. Shalin, M.D., Ph.D.


How can you search the textbook?

For desktop / tablet, you can either use the Google search bar in the upper right corner or visit PathologyOutlines.com and then scroll down to where the 60 chapters are listed, as demonstrated below.

For mobile, visit PathologyOutlines.com, click on “Chapters by Subspecialty” (as demonstrated below) and then click on the subspecialty, chapter and topic.

For any device you can use your favorite browser and type in PathologyOutlines.com in addition to the search term.

24 March 2021: Images of the Week

Here is a selection of new images from our free, online textbook:

Breast > Filariasis

Classic “double barrel” uterus of the adult female worm (Wuchereria bancrofti) with eggs and developing larvae (microfilariae) in a lymph node (H&E, 10x).

Contributed by Bobbi Pritt, M.D.

Stains & molecular markers > Carbonic anhydrase IX

Diffuse circumferential membranous staining in clear cell RCC.

Contributed by Nick Baniak, M.D.

Stomach > MALT lymphoma

Infiltration and distortion of epithelial structures by aggregates of (usually 3 or more) neoplastic lymphoid cells.

Contributed by Kwun Wah Wen, M.D., Ph.D.

Testis & epididymis > Sex cord-stromal tumors > Leydig cell

Leydig cell tumor with sheets of polygonal cells with eosinophilic cytoplasm (H&E stain; 10x magnification).

Contributed by Manju Aron, M.D.

Autopsy & forensics > Therapy related deaths

Autopsy image of a percutaneous biliary catheter in the portal vein. The biliary drain placement was performed to relieve a biliary stricture but the catheter was placed in the portal vein adjacent to the targeted bile duct resulting in hemoperitoneum. The end of the catheter was cut during removal of the liver as this was an unexpected finding at autopsy.

Contributed by Mark A. Giffen, Jr., D.O.


How can you search the textbook?

For desktop / tablet, you can either use the Google search bar in the upper right corner or visit PathologyOutlines.com and then scroll down to where the 60 chapters are listed, as demonstrated below.

For mobile, visit PathologyOutlines.com, click on “Chapters by Subspecialty” (as demonstrated below) and then click on the subspecialty, chapter and topic.

For any device you can use your favorite browser and type in PathologyOutlines.com in addition to the search term.

27 January 2021: Images of the Week

Here is a selection of new images from our free, online textbook:

Microglandular hyperplasia

High power view showing columnar epithelial cells with subnuclear and supranuclear vacuoles, bland nuclei and mucinous cytoplasm, associated with reserve cell hyperplasia; luminal neutrophils in some glands.

Contributed by Gulisa Turashvili, M.D., Ph.D.

Epithelioid hemangioendothelioma

Tumor is comprised of cords, strands and small nests of large endothelial cells with abundant eosinophilic cytoplasm embedded in a myxohyaline stroma.

Contributed by Iva Brčić, M.D., Ph.D. and Bernadette Liegl-Atzwanger, M.D.

Sertoli cell tumor, NOS

Testicular Sertoli cell tumor, NOS (H&E), low magnification, back to back cords of bland, clear cells with abundant cytoplasm.

Contributed by Thomas Ulbright, M.D.

Coombs test / DAT

The results of a patient’s direct antiglobulin (DAT) / Coombs test.

Contributed by Thomas J. Gniadek, M.D., Ph.D.


How can you search the textbook?

For desktop / tablet, you can either use the Google search bar in the upper right corner or visit PathologyOutlines.com and then scroll down to where the 61 chapters are listed, as demonstrated below.

For mobile, visit PathologyOutlines.com, click on “Chapters by Subspecialty” (as demonstrated below) and then click on the subspecialty, chapter and topic.

For any device you can use your favorite browser and type in PathologyOutlines.com in addition to the search term.