20 January 2021: Images of the Week

Here is a selection of new images from our free, online textbook:

Acute mastitis / abscess

Core needle biopsy from a 28 year old lactating woman. A dense inflammatory infiltrate is shown on the left, obscuring underlying breast parenchyma.

Contributed by Kristen E. Muller, D.O.

Prostate specific antigen (PSA)

PSA is focally positive, which is common in more poorly differentiated prostatic adenocarcinoma. Lung adenocarcinoma will not be positive for PSA, so this confirms metastatic prostatic adenocarcinoma. Of note, this patient had a clinical history of a prostatic adenocarcinoma.

Contributed by Heather I-Hsuan Chen-Yost, M.D.

Fibromatosis / fasciitis-like

Papillary thyroid carcinoma with fibromatosis / fasciitis-like stroma: myofibroblastic proliferation within collagenous stromal tissue.

Contributed by Ayana Suzuki, C.T.

Gunshot wounds

Soot deposition, searing of the skin and contusion surrounding the central defect.

Contributed by Lorenzo Gitto, M.D. and Robert Stoppacher, M.D.

How can you search the textbook?

For desktop / tablet, you can either use the Google search bar in the upper right corner or visit PathologyOutlines.com and then scroll down to where the 61 chapters are listed, as demonstrated below.

For mobile, visit PathologyOutlines.com, click on “Chapters by Subspecialty” (as demonstrated below) and then click on the subspecialty, chapter and topic.

For any device you can use your favorite browser and type in PathologyOutlines.com in addition to the search term.

24 November 2020: Images of the Week

Here are just a few of this week’s new images from our free, online textbook:

Bladder cytology -nonneoplastic

Degenerated infected cell with vesicular nucleus showing spider web chromatin (bladder washing, ThinPrep, 60x).

Written by Gong Feng, M.D., Ph.D.Bonnie Choy, M.D.

Metanephric adenofibroma

H&E image showing the epithelial component (bottom) and the stromal component (top).

Written by Rose Chami, M.D.

Trichoepithelioma / trichoblastoma

Cheek biopsy: trichoepithelioma with prominent keratin cyst formation. Note the bland cytologic features, cellular stroma and lack of epithelial stromal clefting (H&E, 100x magnification).

Written by Eleanor Russell-Goldman, M.D., Ph.D.

PAX8

Strong, diffuse nuclear expression of PAX8 in metastatic renal cell carcinoma involving the lung on needle core biopsy.

Written by Kelsey E. McHugh, M.D.

Thyroid gland cytology → Bethesda system, malignant

Papillary thyroid carcinoma, thyroid FNA: intranuclear cytoplasmic inclusion (arrow) and powdery chromatin (Papanicolaou, 40x).

Written by Ayana Suzuki, C.T.Andrey Bychkov, M.D., Ph.D.

How can you search the textbook?

For desktop / tablet, you can either use the Google search bar in the upper right corner or visit PathologyOutlines.com and then scroll down to where the 61 chapters are listed, as demonstrated below.

For mobile, visit PathologyOutlines.com, click on “Chapters by Subspecialty” (as demonstrated below) and then click on the subspecialty, chapter and topic.

For any device you can use your favorite browser and type in PathologyOutlines.com in addition to the search term.